Proof of the Concept to Use a Malignant B Cell Line Drug Screen Strategy for Identification and Weight of Melphalan Resistance Genes in Multiple Myeloma

In a conceptual study of drug resistance we have used a preclinical model of malignant B-cell lines by combining drug induced growth inhibition and gene expression profiling. In the current report a melphalan resistance profile of 19 genes were weighted by microarray data from the MRC Myeloma IX tri...

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Detalles Bibliográficos
Autores principales: Bøgsted, Martin, Bilgrau, Anders E., Wardell, Christopher P., Bertsch, Uta, Schmitz, Alexander, Bødker, Julie S., Kjeldsen, Malene K., Goldschmidt, Hartmut, Morgan, Gareth J., Dybkaer, Karen, Johnsen, Hans E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869769/
https://www.ncbi.nlm.nih.gov/pubmed/24376673
http://dx.doi.org/10.1371/journal.pone.0083252

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