CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling

Ovarian cancer is an inflammation-associated malignancy with a high mortality rate. CXCR2 expressing ovarian cancers are aggressive with poorer outcomes. We therefore investigated molecular mechanisms involved in CXCR2-driven cancer progression by comparing CXCR2 positive and negative ovarian cancer...

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Detalles Bibliográficos
Autores principales: Dong, Yuan-Lin, Kabir, Syeda M., Lee, Eun-Sook, Son, Deok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869803/
https://www.ncbi.nlm.nih.gov/pubmed/24376747
http://dx.doi.org/10.1371/journal.pone.0083789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869803/
https://www.ncbi.nlm.nih.gov/pubmed/24376747
http://dx.doi.org/10.1371/journal.pone.0083789

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