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Nuclear Localization of the Transcriptional Regulator MIER1α Requires Interaction with HDAC1/2 in Breast Cancer Cells

MIER1α is a transcriptional regulator that functions in gene repression through its ability to interact with various chromatin modifiers and transcription factors. We have also shown that MIER1α interacts with ERα and inhibits estrogen-stimulated growth. While MIER1α is localized in the nucleus of M...

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Detalles Bibliográficos
Autores principales: Li, Shengnan, Paterno, Gary D., Gillespie, Laura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869823/
https://www.ncbi.nlm.nih.gov/pubmed/24376786
http://dx.doi.org/10.1371/journal.pone.0084046