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The Heterotaxy gene, GALNT11, glycosylates Notch to orchestrate cilia type and laterality
Heterotaxy (Htx) is a disorder of left-right (LR) body patterning, or laterality, that is associated with major congenital heart disease(1). The etiology and mechanism underlying most human Htx is poorly understood. In vertebrates, laterality is initiated at the embryonic left-right organizer (LRO),...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869867/ https://www.ncbi.nlm.nih.gov/pubmed/24226769 http://dx.doi.org/10.1038/nature12723 |