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CD8(+) Cells Regulate the T helper-17 Response in an Experimental Murine Model of Sjögren Syndrome
This study investigated the regulatory function of CD8(+) cells in T helper (Th) 17 cell-mediated corneal epithelial barrier disruption that develops in a murine desiccating stress (DS) model that resembles Sjögren syndrome. CD8(+) cell depletion promoted generation of IL-17A producing CD4(+) T cell...
Autores principales: | Zhang, X., Schaumburg, C.S., Coursey, T.G., Siemasko, K.F., Volpe, E. A., Gandhi, N.B., Li, D.-Q., Niederkorn, J.Y., Stern, M.E., Pflugfelder, S.C., de Paiva, C.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869878/ https://www.ncbi.nlm.nih.gov/pubmed/24022789 http://dx.doi.org/10.1038/mi.2013.61 |
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