piggyBac Transposon plus Insulators Overcome Epigenetic Silencing to Provide for Stable Signaling Pathway Reporter Cell Lines

Genetically modified hematopoietic progenitors represent an important testing platform for a variety of cell-based therapies, pharmaceuticals, diagnostics and other applications. Stable expression of a transfected gene of interest in the cells is often obstructed by its silencing. DNA transposons of...

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Detalles Bibliográficos
Autores principales: Mossine, Valeri V., Waters, James K., Hannink, Mark, Mawhinney, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869926/
https://www.ncbi.nlm.nih.gov/pubmed/24376882
http://dx.doi.org/10.1371/journal.pone.0085494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869926/
https://www.ncbi.nlm.nih.gov/pubmed/24376882
http://dx.doi.org/10.1371/journal.pone.0085494

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