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Severe malaria is associated with parasite binding to endothelial protein C receptor
Sequestration of Plasmodium falciparum-infected erythrocytes in host blood vessels is a key triggering event in the pathogenesis of severe childhood malaria, which is responsible for about one million deaths every year(1). Sequestration is mediated by specific interactions between members of the P....
Autores principales: | Turner, Louise, Lavstsen, Thomas, Berger, Sanne S., Wang, Christian W., Petersen, Jens E.V., Avril, Marion, Brazier, Andrew J., Freeth, Jim, Jespersen, Jakob S., Nielsen, Morten A., Magistrado, Pamela, Lusingu, John, Smith, Joseph D., Higgins, Matthew K., Theander, Thor G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870021/ https://www.ncbi.nlm.nih.gov/pubmed/23739325 http://dx.doi.org/10.1038/nature12216 |
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