Cargando…

Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives

A total of seven novel benzimidazoles were synthesized by a 4-step reaction starting from 4-fluoro-3-nitrobenzoic acid under relatively mild reaction conditions. The synthesized compounds were screened for their antimycobacterial activity against M. tuberculosis H(37)Rv (MTB-H(37)Rv) and INH-resista...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keng Yoon, Yeong, Ashraf Ali, Mohamed, Choon, Tan Soo, Ismail, Rusli, Chee Wei, Ang, Suresh Kumar, Raju, Osman, Hasnah, Beevi, Farzana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870127/ https://www.ncbi.nlm.nih.gov/pubmed/24381946 http://dx.doi.org/10.1155/2013/926309

Ejemplares similares

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities
por: Almansour, Abdulrahman I., et al.
Publicado: (2014)

Bis-(imidazole/benzimidazole)-pyridine derivatives: synthesis, structure and antimycobacterial activity
por: Antoci, Vasilichia, et al.
Publicado: (2020)

The Chemical Components of Sesbania grandiflora Root and Their Antituberculosis Activity
por: Hasan, Noviany, et al.
Publicado: (2012)

Ethyl 2-(4-bromophenyl)-1-phenyl-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 1-[2-(morpholin-4-yl)ethyl]-2-[4-(morpholin-4-yl)phenyl]-1H-1,3-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

Ethyl 1-phenyl-2-[4-(trifluoromethyl)phenyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 1-phenyl-2-[4-(trifluoromethoxy)phenyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles
por: Jiménez-Juárez, Rogelio, et al.
Publicado: (2020)

Ethyl 2-[4-(dimethylamino)phenyl]-1-phenyl-1H-benzimidazole-5-carboxylate
por: Yeong, Keng Yoon, et al.
Publicado: (2013)

Ethyl 2-(4-bromophenyl)-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazole-5-carboxylate monohydrate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

Ethyl 1-[3-(2-oxopyrrolidin-1-yl)propyl]-2-phenyl-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 1-[2-(morpholin-4-yl)ethyl]-2-[4-(trifluoromethyl)phenyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid
por: Yoon, Yeong Keng, et al.
Publicado: (2013)

Ethyl 2-[4-(morpholin-4-yl)phenyl]-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-1,3-benzimidazole-5-carboxylate monohydrate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 2-(4-chlorophenyl)-1-phenyl-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 2-(4-nitrophenyl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

Ethyl 2-(4-methoxyphenyl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Ethyl 2-[5-(4-fluorophenyl)pyridin-3-yl]-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate
por: Yeong, Keng Yoon, et al.
Publicado: (2013)

Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

Ethyl 2-(4-hydroxy-3-methoxyphenyl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate monohydrate
por: Yoon, Yeong Keng, et al.
Publicado: (2011)

Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate
por: Yoon, Yeong Keng, et al.
Publicado: (2012)

Relationship between cold pressor pain-sensitivity and sleep quality in opioid-dependent males on methadone treatment
por: Zahari, Zalina, et al.
Publicado: (2015)

Novel Thiazolidinone-Azole Hybrids: Design, Synthesis and Antimycobacterial Activity Studies
por: Eroglu, Barbaros, et al.
Publicado: (2016)

Synthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives
por: Almasirad, Ali, et al.
Publicado: (2011)

Antituberculosis activity, phytochemical identification of Costus speciosus (J. Koenig) Sm., Cymbopogon citratus (DC. Ex Nees) Stapf., and Tabernaemontana coronaria (L.) Willd. and their effects on the growth kinetics and cellular integrity of Mycobacterium tuberculosis H37Rv
por: Mohamad, Suriyati, et al.
Publicado: (2018)

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents
por: Zitko, Jan, et al.
Publicado: (2018)

Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation
por: Doležal, Martin, et al.
Publicado: (2009)

Synthesis and Antimycobacterial Activity of 3-Phenyl-1H-indoles
por: Jardim Etchart, Renata, et al.
Publicado: (2021)

2-[(E)-4-(Dimethylamino)benzylidene]indan-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2011)

(E)-2-[4-(Trifluoromethoxy)benzylidene]indan-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2011)

(E)-2-(4-Bromobenzylidene)indan-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2011)

(2E)-2-Benzylidene-5,6-dimethoxyindan-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

5,6-Dimethoxy-4′,5′-diphenylindane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

(E)-2-(3-Chlorobenzylidene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

(E)-2-(3,4-Dimethoxybenzylidene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

(E)-2-[4-(Piperidin-1-yl)benzylidene]-2,3-dihydro-1H-inden-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

(E)-5,6-Dimethoxy-2-(pyridin-4-ylmethylidene)-2,3-dihydro-1H-inden-1-one
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

Enhancement of the antimycobacterial activity of macrophages by ajoene
por: Choi, Ji-Ae, et al.
Publicado: (2017)

A retrospective study on sequential desensitization-rechallenge for antituberculosis drug allergy
por: Thong, Bernard Yu-Hor, et al.
Publicado: (2014)

4′-(4-Bromophenyl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,2′′-indan]-1,3,1′′-trione
por: Wei, Ang Chee, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_h10jmndoksa84jmitbkrv1hvnh