Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C

A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently s...

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Autores principales: Kim, Gun-Wook, Jwa, Seung-Wook, Song, Margaret, Kim, Hoon-Soo, Kim, Byung-Soo, Kim, Moon-Bum, Ko, Hyun-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870218/
https://www.ncbi.nlm.nih.gov/pubmed/24371397
http://dx.doi.org/10.5021/ad.2013.25.4.479
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author Kim, Gun-Wook
Jwa, Seung-Wook
Song, Margaret
Kim, Hoon-Soo
Kim, Byung-Soo
Kim, Moon-Bum
Ko, Hyun-Chang
author_facet Kim, Gun-Wook
Jwa, Seung-Wook
Song, Margaret
Kim, Hoon-Soo
Kim, Byung-Soo
Kim, Moon-Bum
Ko, Hyun-Chang
author_sort Kim, Gun-Wook
collection PubMed
description A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently started narrow-band ultraviolet B phototherapy and topical calcipotriol/betamethasone dipropionate ointment. After this, the psoriasis improved in a slow but comprehensive manner. Our case suggests that physicians should keep in mind the possibility of psoriasis as a side effect of interferon treatment for chronic hepatitis C.
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spelling pubmed-38702182013-12-26 Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C Kim, Gun-Wook Jwa, Seung-Wook Song, Margaret Kim, Hoon-Soo Kim, Byung-Soo Kim, Moon-Bum Ko, Hyun-Chang Ann Dermatol Case Report A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently started narrow-band ultraviolet B phototherapy and topical calcipotriol/betamethasone dipropionate ointment. After this, the psoriasis improved in a slow but comprehensive manner. Our case suggests that physicians should keep in mind the possibility of psoriasis as a side effect of interferon treatment for chronic hepatitis C. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2013-11 2013-11-30 /pmc/articles/PMC3870218/ /pubmed/24371397 http://dx.doi.org/10.5021/ad.2013.25.4.479 Text en Copyright © 2013 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Gun-Wook
Jwa, Seung-Wook
Song, Margaret
Kim, Hoon-Soo
Kim, Byung-Soo
Kim, Moon-Bum
Ko, Hyun-Chang
Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title_full Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title_fullStr Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title_full_unstemmed Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title_short Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C
title_sort extensive psoriasis induced by pegylated interferon alfa-2a and ribavirin in the treatment of chronic hepatitis c
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870218/
https://www.ncbi.nlm.nih.gov/pubmed/24371397
http://dx.doi.org/10.5021/ad.2013.25.4.479
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