The Potent and Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1C19 Reveals a Unique Cross-Reactive Epitope on the bc Loop of Domain II of the Envelope Protein

Following natural dengue virus (DENV) infection, humans produce some antibodies that recognize only the serotype of infection (type specific) and others that cross-react with all four serotypes (cross-reactive). Recent studies with human antibodies indicate that type-specific antibodies at high conc...

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Detalles Bibliográficos
Autores principales: Smith, Scott A., de Alwis, A. Ruklanthi, Kose, Nurgun, Harris, Eva, Ibarra, Kristie D., Kahle, Kristen M., Pfaff, Jennifer M., Xiang, Xiaoxiao, Doranz, Benjamin J., de Silva, Aravinda M., Austin, S. Kyle, Sukupolvi-Petty, Soila, Diamond, Michael S., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870244/
https://www.ncbi.nlm.nih.gov/pubmed/24255124
http://dx.doi.org/10.1128/mBio.00873-13

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