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TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic

The TNF superfamily member TWEAK (TNFSF12) is a multifunctional cytokine implicated in physiological tissue regeneration and wound repair. TWEAK is initially synthesized as a membrane-anchored protein, but furin cleavage within the stalk region can generate a secreted TWEAK isoform. Both TWEAK isofo...

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Detalles Bibliográficos
Autores principales:	Cheng, Emily, Armstrong, Cheryl L., Galisteo, Rebeca, Winkles, Jeffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870272/ https://www.ncbi.nlm.nih.gov/pubmed/24391646 http://dx.doi.org/10.3389/fimmu.2013.00473

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