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Type I pyridoxal 5′-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines

BACKGROUND: Pyridoxal 5′-phosphate (PLP)-dependent enzymes of fold type I, the most studied structural class of the PLP-dependent enzyme superfamily, are known to exist as stand-alone homodimers or homotetramers. These enzymes have been found also embedded in multimodular and multidomain assembly li...

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Detalles Bibliográficos
Autores principales: Milano, Teresa, Paiardini, Alessandro, Grgurina, Ingeborg, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870968/
https://www.ncbi.nlm.nih.gov/pubmed/24148833
http://dx.doi.org/10.1186/1472-6807-13-26