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The Molecular Pathogenesis of Pituitary Adenomas: An Update

Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adeno...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaobing, Zhang, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871038/
https://www.ncbi.nlm.nih.gov/pubmed/24396688
http://dx.doi.org/10.3803/EnM.2013.28.4.245
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author Jiang, Xiaobing
Zhang, Xun
author_facet Jiang, Xiaobing
Zhang, Xun
author_sort Jiang, Xiaobing
collection PubMed
description Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs.
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spelling pubmed-38710382014-01-06 The Molecular Pathogenesis of Pituitary Adenomas: An Update Jiang, Xiaobing Zhang, Xun Endocrinol Metab (Seoul) Review Article Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs. Korean Endocrine Society 2013-12 2013-12-12 /pmc/articles/PMC3871038/ /pubmed/24396688 http://dx.doi.org/10.3803/EnM.2013.28.4.245 Text en Copyright © 2013 Korean Endocrine Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Jiang, Xiaobing
Zhang, Xun
The Molecular Pathogenesis of Pituitary Adenomas: An Update
title The Molecular Pathogenesis of Pituitary Adenomas: An Update
title_full The Molecular Pathogenesis of Pituitary Adenomas: An Update
title_fullStr The Molecular Pathogenesis of Pituitary Adenomas: An Update
title_full_unstemmed The Molecular Pathogenesis of Pituitary Adenomas: An Update
title_short The Molecular Pathogenesis of Pituitary Adenomas: An Update
title_sort molecular pathogenesis of pituitary adenomas: an update
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871038/
https://www.ncbi.nlm.nih.gov/pubmed/24396688
http://dx.doi.org/10.3803/EnM.2013.28.4.245
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