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The Molecular Pathogenesis of Pituitary Adenomas: An Update
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adeno...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871038/ https://www.ncbi.nlm.nih.gov/pubmed/24396688 http://dx.doi.org/10.3803/EnM.2013.28.4.245 |
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author | Jiang, Xiaobing Zhang, Xun |
author_facet | Jiang, Xiaobing Zhang, Xun |
author_sort | Jiang, Xiaobing |
collection | PubMed |
description | Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs. |
format | Online Article Text |
id | pubmed-3871038 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Korean Endocrine Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-38710382014-01-06 The Molecular Pathogenesis of Pituitary Adenomas: An Update Jiang, Xiaobing Zhang, Xun Endocrinol Metab (Seoul) Review Article Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs. Korean Endocrine Society 2013-12 2013-12-12 /pmc/articles/PMC3871038/ /pubmed/24396688 http://dx.doi.org/10.3803/EnM.2013.28.4.245 Text en Copyright © 2013 Korean Endocrine Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Jiang, Xiaobing Zhang, Xun The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title | The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title_full | The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title_fullStr | The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title_full_unstemmed | The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title_short | The Molecular Pathogenesis of Pituitary Adenomas: An Update |
title_sort | molecular pathogenesis of pituitary adenomas: an update |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871038/ https://www.ncbi.nlm.nih.gov/pubmed/24396688 http://dx.doi.org/10.3803/EnM.2013.28.4.245 |
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