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Chemical Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with Substituted Amino Moiety

Novel pleuromutilin derivatives designed based on the structure of valnemulin were synthesized and evaluated for their in vitro antibacterial activities. These pleuromutilin derivatives with substituted amino moiety exhibited excellent activities against methicillin-resistant Staphylococcus aureus,...

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Detalles Bibliográficos
Autores principales: Shang, Ruofeng, Wang, Shengyu, Xu, Ximing, Yi, Yunpeng, Guo, Wenzhu, YuLiu, Liang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871055/
https://www.ncbi.nlm.nih.gov/pubmed/24376551
http://dx.doi.org/10.1371/journal.pone.0082595