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Chemical Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with Substituted Amino Moiety
Novel pleuromutilin derivatives designed based on the structure of valnemulin were synthesized and evaluated for their in vitro antibacterial activities. These pleuromutilin derivatives with substituted amino moiety exhibited excellent activities against methicillin-resistant Staphylococcus aureus,...
Autores principales: | Shang, Ruofeng, Wang, Shengyu, Xu, Ximing, Yi, Yunpeng, Guo, Wenzhu, YuLiu, Liang, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871055/ https://www.ncbi.nlm.nih.gov/pubmed/24376551 http://dx.doi.org/10.1371/journal.pone.0082595 |
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