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Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma
BACKGROUND: When T cells infiltrate the tumor environment they encounter a myriad of metabolic stressors including hypoxia. Overcoming the limitations imposed by an inadequate tumor vasculature that contributes to these stressors may be a crucial step to immune cells mounting an effective anti-tumor...
Autores principales: | Townsend, Katelin N., Spowart, Jaeline E., Huwait, Hassan, Eshragh, Sima, West, Nathan R., Elrick, Mary A., Kalloger, Steve E., Anglesio, Michael, Watson, Peter H., Huntsman, David G., Lum, Julian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871161/ https://www.ncbi.nlm.nih.gov/pubmed/24376535 http://dx.doi.org/10.1371/journal.pone.0082406 |
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