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Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs()
The protease fibroblast activation protein (FAP) is a specific marker of activated mesenchymal cells in tumour stroma and fibrotic liver. A specific, reliable FAP enzyme assay has been lacking. FAP's unique and restricted cleavage of the post proline bond was exploited to generate a new specifi...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871272/ https://www.ncbi.nlm.nih.gov/pubmed/24371721 http://dx.doi.org/10.1016/j.fob.2013.12.001 |