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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells
Heterogeneity within pluripotent stem cell (PSC) populations is indicative of dynamic changes that occur when cells drift between different states. Although the role of metastability in PSCs is unclear, it appears to reflect heterogeneity in cell signaling. Using the Fucci cell-cycle indicator syste...
Autores principales: | Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871385/ https://www.ncbi.nlm.nih.gov/pubmed/24371808 http://dx.doi.org/10.1016/j.stemcr.2013.10.009 |
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