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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells

Heterogeneity within pluripotent stem cell (PSC) populations is indicative of dynamic changes that occur when cells drift between different states. Although the role of metastability in PSCs is unclear, it appears to reflect heterogeneity in cell signaling. Using the Fucci cell-cycle indicator syste...

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Detalles Bibliográficos
Autores principales: Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871385/
https://www.ncbi.nlm.nih.gov/pubmed/24371808
http://dx.doi.org/10.1016/j.stemcr.2013.10.009