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Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells

Joint injury and osteoarthritis affect millions of people worldwide, but attempts to generate articular cartilage using adult stem/progenitor cells have been unsuccessful. We hypothesized that recapitulation of the human developmental chondrogenic program using pluripotent stem cells (PSCs) may repr...

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Detalles Bibliográficos
Autores principales: Wu, Ling, Bluguermann, Carolina, Kyupelyan, Levon, Latour, Brooke, Gonzalez, Stephanie, Shah, Saumya, Galic, Zoran, Ge, Sundi, Zhu, Yuhua, Petrigliano, Frank A., Nsair, Ali, Miriuka, Santiago G., Li, Xinmin, Lyons, Karen M., Crooks, Gay M., McAllister, David R., Van Handel, Ben, Adams, John S., Evseenko, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871393/
https://www.ncbi.nlm.nih.gov/pubmed/24371811
http://dx.doi.org/10.1016/j.stemcr.2013.10.012