Interleukin-1β and Interleukin-1 Receptor Antagonist Appear in Grey Matter Additionally to White Matter Lesions during Experimental Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) has been mainly attributed to white matter (WM) pathology. However, recent evidence indicated the presence of grey matter (GM) lesions. One of the principal mediators of inflammatory processes is interleukin-1β (IL-1β), which is known to play a role in MS pathogen...

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Detalles Bibliográficos
Autores principales: Prins, Marloes, Eriksson, Charlotta, Wierinckx, Anne, Bol, John G. J. M., Binnekade, Rob, Tilders, Fred J. H., Van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871572/
https://www.ncbi.nlm.nih.gov/pubmed/24376764
http://dx.doi.org/10.1371/journal.pone.0083835

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