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Dysregulated Striatal Neuronal Processing and Impaired Motor Behavior in Mice Lacking Huntingtin Interacting Protein 14 (HIP14)

Palmitoyl acyl transferases (PATs) play a critical role in protein trafficking and function. Huntingtin interacting protein 14 (HIP14) is a PAT that acts on proteins associated with neuronal transmission, suggesting that deficient protein palmitoylation by HIP14, which occurs in the YAC128 model of...

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Detalles Bibliográficos
Autores principales: Estrada-Sánchez, Ana María, Barton, Scott J., Burroughs, Courtney L., Doyle, Amanda R., Rebec, George V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871627/
https://www.ncbi.nlm.nih.gov/pubmed/24376823
http://dx.doi.org/10.1371/journal.pone.0084537