Cargando…
ROS Detoxification and Proinflammatory Cytokines Are Linked by p38 MAPK Signaling in a Model of Mature Astrocyte Activation
Astrocytes are the most abundant glial cell in the retinal nerve fiber layer (NFL) and optic nerve head (ONH), and perform essential roles in maintaining retinal ganglion cell (RGC) detoxification and homeostasis. Mature astrocytes are relatively quiescent, but rapidly undergo a phenotypic switch in...
Autores principales: | Nahirnyj, Adrian, Livne-Bar, Izhar, Guo, Xiaoxin, Sivak, Jeremy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871647/ https://www.ncbi.nlm.nih.gov/pubmed/24376630 http://dx.doi.org/10.1371/journal.pone.0083049 |
Ejemplares similares
-
Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis
por: Livne-Bar, Izhar, et al.
Publicado: (2016) -
An inducible rodent glaucoma model that exhibits gradual sustained increase in intraocular pressure with distinct inner retina and optic nerve inflammation
por: Mathew, David J., et al.
Publicado: (2021) -
Detoxification of LTA by intracanal medication: analysis by macrophages proinflammatory cytokines production
por: de Oliveira, Luciane Dias, et al.
Publicado: (2022) -
Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway
por: Liu, Liping, et al.
Publicado: (2017) -
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14
por: Alqawlaq, Samih, et al.
Publicado: (2020)