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Microfluidic Generated EGF-Gradients Induce Chemokinesis of Transplantable Retinal Progenitor Cells via the JAK/STAT and PI3Kinase Signaling Pathways

A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is important to define the molecular and biochemical mechanis...

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Detalles Bibliográficos
Autores principales: Unachukwu, Uchenna J., Sauane, Moira, Vazquez, Maribel, Redenti, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871684/
https://www.ncbi.nlm.nih.gov/pubmed/24376770
http://dx.doi.org/10.1371/journal.pone.0083906