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Three Dimensional Pharmacophore Modelling of Monoamine oxidase-A (MAO-A) inhibitors

Flavoprotein monoamine oxidase is located on the outer membrane of mitochondria. It catalyzes oxidative deamination of monoamine neurotransmitters such as serotonin, norepinephrine and dopamine and hence is a target enzyme for antidepressant drugs. MAO (mono amine oxidase) has two isoforms, namely M...

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Detalles Bibliográficos
Autores principales: Sairam, Kalapatapu V.V.M., Khar, Roop K., Mukherjee, Rama, Jain, Swatantra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871892/