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Three Dimensional Pharmacophore Modelling of Monoamine oxidase-A (MAO-A) inhibitors
Flavoprotein monoamine oxidase is located on the outer membrane of mitochondria. It catalyzes oxidative deamination of monoamine neurotransmitters such as serotonin, norepinephrine and dopamine and hence is a target enzyme for antidepressant drugs. MAO (mono amine oxidase) has two isoforms, namely M...
Autores principales: | Sairam, Kalapatapu V.V.M., Khar, Roop K., Mukherjee, Rama, Jain, Swatantra K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871892/ |
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