Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer’s disease

Amyloid β (Aβ) accumulation is considered the main culprit in the pathogenesis of Alzheimer’s disease (AD). Recent studies suggest that decreasing Aβ production at very early stages of AD could be a promising strategy to slow down disease progression. Serotonin 5-HT(4) receptor activation stimulates...

Descripción completa

Detalles Bibliográficos
Autores principales: Giannoni, Patrizia, Gaven, Florence, de Bundel, Dimitri, Baranger, Kevin, Marchetti-Gauthier, Evelyne, Roman, François S., Valjent, Emmanuel, Marin, Philippe, Bockaert, Joël, Rivera, Santiago, Claeysen, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871961/
https://www.ncbi.nlm.nih.gov/pubmed/24399967
http://dx.doi.org/10.3389/fnagi.2013.00096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871961/
https://www.ncbi.nlm.nih.gov/pubmed/24399967
http://dx.doi.org/10.3389/fnagi.2013.00096

Ejemplares similares