Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS

Microglia and reactive astrocytes accumulate in the spinal cord of rats expressing the Amyotrophic lateral sclerosis (ALS)-linked SOD1 (G93A) mutation. We previously reported that the rapid progression of paralysis in ALS rats is associated with the appearance of proliferative astrocyte-like cells t...

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Detalles Bibliográficos
Autores principales: Trias, Emiliano, Díaz-Amarilla, Pablo, Olivera-Bravo, Silvia, Isasi, Eugenia, Drechsel, Derek A., Lopez, Nathan, Bradford, C. Samuel, Ireton, Kyle E., Beckman, Joseph S., Barbeito, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871969/
https://www.ncbi.nlm.nih.gov/pubmed/24399933
http://dx.doi.org/10.3389/fncel.2013.00274

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