Cargando…
Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents
Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, a...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872012/ https://www.ncbi.nlm.nih.gov/pubmed/24381750 http://dx.doi.org/10.1155/2013/724781 |
_version_ | 1782296909246889984 |
---|---|
author | Grotti Clemente, Ana Paula Molin Netto, Bárbara Dal Ganen, Aline di Piano Tock, Lian Arisa Caranti, Danielle de Mello, Marco Túlio Tufik, Sergio Dâmaso, Ana R. |
author_facet | Grotti Clemente, Ana Paula Molin Netto, Bárbara Dal Ganen, Aline di Piano Tock, Lian Arisa Caranti, Danielle de Mello, Marco Túlio Tufik, Sergio Dâmaso, Ana R. |
author_sort | Grotti Clemente, Ana Paula |
collection | PubMed |
description | Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, and insulin resistance were analyzed. Visceral and subcutaneous fat were measured by ultrasound and body composition by plesthysmography. Results. The NAFLD adolescents had significantly higher values for body mass, BMI-for-age, BMI, total fat, waist circumference, and visceral fat when compared with non-NAFLD obese adolescents in both genders. Moreover, there were significant positive correlations between visceral fat with the variables BMI-for-age (r = 0.325,), TG (r = 0.277), AST (r = 0.509), ALT (r = 0.519), WC (r = 0.390), and visceral/subcutaneous ratio (r = 0.790) for NAFLD group. Total fat, triglycerides, and visceral fat were the independent predictors to NAFLD. Analysis of the ROC curves revealed cut-off points of visceral fat of 4.47 cm for girls and 4.21 cm for boys. Conclusions. The results may suggest that abdominal ultrasonography procedure may be a safe alternative method of assessing visceral adiposity aiming to be considered to the development of preventive and treatment strategies in obese individuals. This clinial trial is registered with ClinicalTrial.gov (NCT01358773). |
format | Online Article Text |
id | pubmed-3872012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-38720122013-12-31 Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents Grotti Clemente, Ana Paula Molin Netto, Bárbara Dal Ganen, Aline di Piano Tock, Lian Arisa Caranti, Danielle de Mello, Marco Túlio Tufik, Sergio Dâmaso, Ana R. J Nutr Metab Clinical Study Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, and insulin resistance were analyzed. Visceral and subcutaneous fat were measured by ultrasound and body composition by plesthysmography. Results. The NAFLD adolescents had significantly higher values for body mass, BMI-for-age, BMI, total fat, waist circumference, and visceral fat when compared with non-NAFLD obese adolescents in both genders. Moreover, there were significant positive correlations between visceral fat with the variables BMI-for-age (r = 0.325,), TG (r = 0.277), AST (r = 0.509), ALT (r = 0.519), WC (r = 0.390), and visceral/subcutaneous ratio (r = 0.790) for NAFLD group. Total fat, triglycerides, and visceral fat were the independent predictors to NAFLD. Analysis of the ROC curves revealed cut-off points of visceral fat of 4.47 cm for girls and 4.21 cm for boys. Conclusions. The results may suggest that abdominal ultrasonography procedure may be a safe alternative method of assessing visceral adiposity aiming to be considered to the development of preventive and treatment strategies in obese individuals. This clinial trial is registered with ClinicalTrial.gov (NCT01358773). Hindawi Publishing Corporation 2013 2013-12-07 /pmc/articles/PMC3872012/ /pubmed/24381750 http://dx.doi.org/10.1155/2013/724781 Text en Copyright © 2013 Ana Paula Grotti Clemente et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Grotti Clemente, Ana Paula Molin Netto, Bárbara Dal Ganen, Aline di Piano Tock, Lian Arisa Caranti, Danielle de Mello, Marco Túlio Tufik, Sergio Dâmaso, Ana R. Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title | Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title_full | Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title_fullStr | Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title_full_unstemmed | Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title_short | Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents |
title_sort | cut-off values of visceral adiposity to predict nafld in brazilian obese adolescents |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872012/ https://www.ncbi.nlm.nih.gov/pubmed/24381750 http://dx.doi.org/10.1155/2013/724781 |
work_keys_str_mv | AT grotticlementeanapaula cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT molinnettobarbaradal cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT ganenalinedipiano cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT tocklian cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT arisacarantidanielle cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT demellomarcotulio cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT tufiksergio cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents AT damasoanar cutoffvaluesofvisceraladipositytopredictnafldinbrazilianobeseadolescents |