Cargando…

(+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death

Human pancreatic tumors are known to be highly resistant to nutrient starvation, and this prolongs their survival in the hypovascular (austere) tumor microenvironment. Agents that retard this tolerance to nutrient starvation represent a novel antiausterity strategy in anticancer drug discovery. (+)-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ueda, Jun-ya, Athikomkulchai, Sirivan, Miyatake, Ryuta, Saiki, Ikuo, Esumi, Hiroyasu, Awale, Suresh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872082/ https://www.ncbi.nlm.nih.gov/pubmed/24379655 http://dx.doi.org/10.2147/DDDT.S52168

Ejemplares similares

Antiausterity Activity of Secondary Metabolites from the Roots of Ferula hezarlalehzarica against the PANC-1 Human Pancreatic Cancer Cell Line
por: Alilou, Mostafa, et al.
Publicado: (2020)

Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti‐Austerity Activity against Human PANC‐1 Pancreatic Cancer Cells
por: Alexander, Benjamin E., et al.
Publicado: (2019)

Michellamines A(6) and A(7), and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells
por: Lombe, Blaise Kimbadi, et al.
Publicado: (2018)

Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora
por: Sun, Sijia, et al.
Publicado: (2021)

Wound healing activity of Pluchea indica leaf extract in oral mucosal cell line and oral spray formulation containing nanoparticles of the extract
por: Buranasukhon, Wiphupat, et al.
Publicado: (2017)

Chemical Constituents of Callistemon subulatus and Their Anti-Pancreatic Cancer Activity against Human PANC-1 Cell Line
por: Maneenet, Juthamart, et al.
Publicado: (2022)

Ultraviolet Radiation Protective and Anti-Inflammatory Effects of Kaempferia galanga L. Rhizome Oil and Microemulsion: Formulation, Characterization, and Hydrogel Preparation
por: Chittasupho, Chuda, et al.
Publicado: (2022)

THE PANC 3 SCORE PREDICTING SEVERITY OF ACUTE PANCREATITIS
por: BEDUSCHI, Murilo Gamba, et al.
Publicado: (2016)

Phenylethanoid Glycoside-Enriched Extract Prepared from Clerodendrum chinense Leaf Inhibits A549 Lung Cancer Cell Migration and Apoptosis Induction through Enhancing ROS Production
por: Chittasupho, Chuda, et al.
Publicado: (2023)

Electron Beam Irradiation Cross-Linked Hydrogel Patches Loaded with Red Onion Peel Extract for Transdermal Drug Delivery: Formulation, Characterization, Cytocompatibility, and Skin Permeation
por: Uttayarat, Pimpon, et al.
Publicado: (2023)

Assessment of PANC3 Score in Predicting Severity of Acute Pancreatitis
por: Shah, Avreen Singh, et al.
Publicado: (2017)

In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
por: Khoshkholgh-Sima, Baharak, et al.
Publicado: (2015)

Emerging Contribution of PancRNAs in Cancer
por: Mercatelli, Neri, et al.
Publicado: (2020)

Phytochemical Analysis, Antioxidant, and Wound Healing Activity of Pluchea indica L. (Less) Branch Extract Nanoparticles
por: Chiangnoon, Rattanakorn, et al.
Publicado: (2022)

Glycolysis in Panc-1 human pancreatic cancer cells is inhibited by everolimus
por: LIU, LING, et al.
Publicado: (2013)

P86 PANC Study - Pancreatitis: A National Cohort Study
Publicado: (2021)

Effect of quercetin on apoptosis of PANC-1 cells
por: Lee, Joo Hyun, et al.
Publicado: (2013)

Effects of disulfiram on apoptosis in PANC-1 human pancreatic cancer cell line
por: Dastjerdi, M. Nikbakht, et al.
Publicado: (2014)

Cytotoxic effect of pyocyanin on human pancreatic cancer cell line (Panc-1)
por: Moayedi, Aylin, et al.
Publicado: (2018)

Metabolic characterization of invaded cells of the pancreatic cancer cell line, PANC‐1
por: Fujita, Mayumi, et al.
Publicado: (2017)

Autophagic Cell Death and Cancer
por: Shimizu, Shigeomi, et al.
Publicado: (2014)

Development of Jelly Loaded with Nanogel Containing Natural L-Dopa from Mucuna pruriens Seed Extract for Neuroprotection in Parkinson’s Disease
por: Chittasupho, Chuda, et al.
Publicado: (2022)

Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice
por: Xiao, Z, et al.
Publicado: (2014)

Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells
por: Sood, Nimil, et al.
Publicado: (2013)

Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells
por: Hofer, M D, et al.
Publicado: (2004)

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
por: Santoni, M, et al.
Publicado: (2013)

Isoalantolactone Induces Reactive Oxygen Species Mediated Apoptosis in Pancreatic Carcinoma PANC-1 Cells
por: Khan, Muhammad, et al.
Publicado: (2012)

Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo
por: Cheng, Hao, et al.
Publicado: (2017)

Silencing of Carboxypeptidase E expression inhibits proliferation and invasion of Panc-1 pancreatic cancer cells
por: Lou, Hong, et al.
Publicado: (2022)

MicroRNAs Targeting Caspase-3 and -7 in PANC-1 Cells
por: Park, Jong Kook, et al.
Publicado: (2018)

Selection and Optimization of a Bioink Based on PANC-1- Plasma/Alginate/Methylcellulose for Pancreatic Tumour Modelling
por: Banda Sánchez, Cristina, et al.
Publicado: (2023)

Salinomycin induces autophagic cell death in salinomycin-sensitive melanoma cells through inhibition of autophagic flux
por: Liu, Yajing, et al.
Publicado: (2020)

Natural agents mediated autophagic signal networks in cancer
por: Sohn, Eun Jung, et al.
Publicado: (2017)

PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets
por: Khakinezhad Tehrani, Fatemeh, et al.
Publicado: (2021)

Autosis and autophagic cell death: the dark side of autophagy
por: Liu, Y, et al.
Publicado: (2015)

Autophagic Cell Death During Development – Ancient and Mysterious
por: Schwartz, Lawrence M.
Publicado: (2021)

Silencing of the integrin-linked kinase gene suppresses the proliferation, migration and invasion of pancreatic cancer cells (Panc-1)
por: Zhu, Xiang-Yu, et al.
Publicado: (2012)

Acetylshikonin Inhibits Human Pancreatic PANC-1 Cancer Cell Proliferation by Suppressing the NF-κB Activity
por: Cho, Seok-Cheol, et al.
Publicado: (2015)

Phage Display-Based Homing Peptide-Daunomycin Conjugates for Selective Drug Targeting to PANC-1 Pancreatic Cancer
por: Dókus, Levente E., et al.
Publicado: (2020)

Development of PancRISK, a urine biomarker-based risk score for stratified screening of pancreatic cancer patients
por: Blyuss, Oleg, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cgrdf68371j97jf8pk6fdsqrnc