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(+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death

Human pancreatic tumors are known to be highly resistant to nutrient starvation, and this prolongs their survival in the hypovascular (austere) tumor microenvironment. Agents that retard this tolerance to nutrient starvation represent a novel antiausterity strategy in anticancer drug discovery. (+)-...

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Detalles Bibliográficos
Autores principales:	Ueda, Jun-ya, Athikomkulchai, Sirivan, Miyatake, Ryuta, Saiki, Ikuo, Esumi, Hiroyasu, Awale, Suresh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872082/ https://www.ncbi.nlm.nih.gov/pubmed/24379655 http://dx.doi.org/10.2147/DDDT.S52168

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