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Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years

Background. Gastroduodenal ulcer bleeding is a common medical emergency. The aim of this study was to analyze the characteristics of bleeding episodes and to identify changes in the clinical trends over seven years. Methods. Retrospective observational clinical study on a cohort of 272 consecutive a...

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Autores principales: Lauret, Eugenia, Herrero, Jesús, Blanco, Lorena, Castaño, Olegario, Rodriguez, Maria, Pérez, Isabel, Alvarez, Verónica, Suárez, Adolfo, Rodrigo, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872235/
https://www.ncbi.nlm.nih.gov/pubmed/24385981
http://dx.doi.org/10.1155/2013/584540
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author Lauret, Eugenia
Herrero, Jesús
Blanco, Lorena
Castaño, Olegario
Rodriguez, Maria
Pérez, Isabel
Alvarez, Verónica
Suárez, Adolfo
Rodrigo, Luis
author_facet Lauret, Eugenia
Herrero, Jesús
Blanco, Lorena
Castaño, Olegario
Rodriguez, Maria
Pérez, Isabel
Alvarez, Verónica
Suárez, Adolfo
Rodrigo, Luis
author_sort Lauret, Eugenia
collection PubMed
description Background. Gastroduodenal ulcer bleeding is a common medical emergency. The aim of this study was to analyze the characteristics of bleeding episodes and to identify changes in the clinical trends over seven years. Methods. Retrospective observational clinical study on a cohort of 272 consecutive adult patients with peptic ulcer bleeding, during the 2006–2012 period. Results. Mean annual admission rate was 12.8 per 100.000 inhabitants. Men were predominant (71%), with a mean age of 66.6 years. Comorbidities were present in 131 cases (48.2%) and 156 patients (57.4%) had received ulcerogenic drugs. Duodenal ulcer was the commonest location (61%). Endoscopic therapy was necessary in 183 cases (67.3%) and rebleeding occurred in 30 patients (11%). Overall mortality rate was 5.5%, with a significant association with the presence of comorbidities (P < 0.01). There were no differences in trends of annual hospitalization, clinical features at presentation, and outcomes during this 7-years period. Conclusions. Annual hospitalization rates and prognosis of peptic ulcer bleeding have remained unchanged in the study period. This may be due to the fact that the effect of improved approach on this condition is probably counteracted by risk factors such as older age, severe comorbidities, and ulcerogenic drugs consumption, which have also remained stable over recent years.
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spelling pubmed-38722352014-01-02 Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years Lauret, Eugenia Herrero, Jesús Blanco, Lorena Castaño, Olegario Rodriguez, Maria Pérez, Isabel Alvarez, Verónica Suárez, Adolfo Rodrigo, Luis Gastroenterol Res Pract Clinical Study Background. Gastroduodenal ulcer bleeding is a common medical emergency. The aim of this study was to analyze the characteristics of bleeding episodes and to identify changes in the clinical trends over seven years. Methods. Retrospective observational clinical study on a cohort of 272 consecutive adult patients with peptic ulcer bleeding, during the 2006–2012 period. Results. Mean annual admission rate was 12.8 per 100.000 inhabitants. Men were predominant (71%), with a mean age of 66.6 years. Comorbidities were present in 131 cases (48.2%) and 156 patients (57.4%) had received ulcerogenic drugs. Duodenal ulcer was the commonest location (61%). Endoscopic therapy was necessary in 183 cases (67.3%) and rebleeding occurred in 30 patients (11%). Overall mortality rate was 5.5%, with a significant association with the presence of comorbidities (P < 0.01). There were no differences in trends of annual hospitalization, clinical features at presentation, and outcomes during this 7-years period. Conclusions. Annual hospitalization rates and prognosis of peptic ulcer bleeding have remained unchanged in the study period. This may be due to the fact that the effect of improved approach on this condition is probably counteracted by risk factors such as older age, severe comorbidities, and ulcerogenic drugs consumption, which have also remained stable over recent years. Hindawi Publishing Corporation 2013 2013-12-09 /pmc/articles/PMC3872235/ /pubmed/24385981 http://dx.doi.org/10.1155/2013/584540 Text en Copyright © 2013 Eugenia Lauret et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Lauret, Eugenia
Herrero, Jesús
Blanco, Lorena
Castaño, Olegario
Rodriguez, Maria
Pérez, Isabel
Alvarez, Verónica
Suárez, Adolfo
Rodrigo, Luis
Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title_full Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title_fullStr Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title_full_unstemmed Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title_short Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
title_sort epidemiological clinical features and evolution of gastroduodenal ulcer bleeding in a tertiary care hospital in spain, during the last seven years
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872235/
https://www.ncbi.nlm.nih.gov/pubmed/24385981
http://dx.doi.org/10.1155/2013/584540
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