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Type I Interferons as Stimulators of DC-Mediated Cross-Priming: Impact on Anti-Tumor Response

Induction of potent tumor-specific cytotoxic T-cell responses is a fundamental objective in anticancer therapeutic strategies. This event requires that antigen-presenting cells present tumor-associated antigens (Ag) on their MHC class-I molecule, in a process termed cross-presentation. Dendritic cel...

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Detalles Bibliográficos
Autores principales: Schiavoni, Giovanna, Mattei, Fabrizio, Gabriele, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872318/
https://www.ncbi.nlm.nih.gov/pubmed/24400008
http://dx.doi.org/10.3389/fimmu.2013.00483