Polymorphisms of MTHFR Associated with Higher Relapse/Death Ratio and Delayed Weekly MTX Administration in Pediatric Lymphoid Malignancies

Backgrounds. Outcome of childhood malignancy has been improved mostly due to the advances in diagnostic techniques and treatment strategies. While methotrexate (MTX) related polymorphisms have been under investigation in childhood malignancies, many controversial results have been offered. Objective...

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Detalles Bibliográficos
Autores principales: Fukushima, Hiroko, Fukushima, Takashi, Sakai, Aiko, Suzuki, Ryoko, Nakajima-Yamaguchi, Ryoko, Kobayashi, Chie, Iwabuchi, Atsushi, Saito, Makoto, Yoshimi, Ai, Nakao, Tomohei, Kato, Keisuke, Tsuchida, Masahiro, Takahashi, Hideto, Koike, Kazutoshi, Kiyokawa, Nobutaka, Noguchi, Emiko, Sumazaki, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872414/
https://www.ncbi.nlm.nih.gov/pubmed/24386571
http://dx.doi.org/10.1155/2013/238528

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