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Antiproliferative and Apoptotic Effects of a Specific Antiprostate Stem Cell Single Chain Antibody on Human Prostate Cancer Cells

Prostate stem cell antigen (PSCA) is a highly glycosylated cell surface protein which is overexpressed in several malignancies including prostate, pancreas, and urinary bladder cancers. Tumor suppression has been reported by anti-PSCA antibody. Small and high affinity single chain antibodies (scFv)...

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Detalles Bibliográficos
Autores principales: Nejatollahi, Foroogh, Abdi, Soghra, Asgharpour, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872421/
https://www.ncbi.nlm.nih.gov/pubmed/24391668
http://dx.doi.org/10.1155/2013/839831