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Heparanase and Autoimmune Diabetes
Heparanase (Hpse) is the only known mammalian endo-β-d-glucuronidase that degrades the glycosaminoglycan heparan sulfate (HS), found attached to the core proteins of heparan sulfate proteoglycans (HSPGs). Hpse plays a homeostatic role in regulating the turnover of cell-associated HS and also degrade...
Autores principales: | Simeonovic, Charmaine J., Ziolkowski, Andrew F., Wu, Zuopeng, Choong, Fui Jiun, Freeman, Craig, Parish, Christopher R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872651/ https://www.ncbi.nlm.nih.gov/pubmed/24421779 http://dx.doi.org/10.3389/fimmu.2013.00471 |
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