Estimating the Diversity, Completeness, and Cross-Reactivity of the T Cell Repertoire

In order to recognize and combat a diverse array of pathogens the immune system has a large repertoire of T cells having unique T cell receptors (TCRs) with only a few clones specific for any given antigen. We discuss how the number of different possible TCRs encoded in the genome (the potential rep...

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Detalles Bibliográficos
Autores principales: Zarnitsyna, Veronika I., Evavold, Brian D., Schoettle, Louis N., Blattman, Joseph N., Antia, Rustom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872652/
https://www.ncbi.nlm.nih.gov/pubmed/24421780
http://dx.doi.org/10.3389/fimmu.2013.00485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872652/
https://www.ncbi.nlm.nih.gov/pubmed/24421780
http://dx.doi.org/10.3389/fimmu.2013.00485

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