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Estimating the Diversity, Completeness, and Cross-Reactivity of the T Cell Repertoire
In order to recognize and combat a diverse array of pathogens the immune system has a large repertoire of T cells having unique T cell receptors (TCRs) with only a few clones specific for any given antigen. We discuss how the number of different possible TCRs encoded in the genome (the potential rep...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872652/ https://www.ncbi.nlm.nih.gov/pubmed/24421780 http://dx.doi.org/10.3389/fimmu.2013.00485 |