A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml

Fondaparinux sodium is a synthetic, sulfated pentasaccharide, selective factor Xa inhibitor, a safe and effective antithrombotic agent indicated for preventing thrombus formation in patients with acute coronary syndromes, including those with ST-segment elevation myocardial infarction (STEMI), non-S...

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Autores principales: Tandon, Vishal R., Sharma, Sudhaa, Mahajan, Shagun, Mahajan, Annil, Khajuria, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872673/
https://www.ncbi.nlm.nih.gov/pubmed/24381468
http://dx.doi.org/10.4103/0976-7800.122260
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author Tandon, Vishal R.
Sharma, Sudhaa
Mahajan, Shagun
Mahajan, Annil
Khajuria, Vijay
author_facet Tandon, Vishal R.
Sharma, Sudhaa
Mahajan, Shagun
Mahajan, Annil
Khajuria, Vijay
author_sort Tandon, Vishal R.
collection PubMed
description Fondaparinux sodium is a synthetic, sulfated pentasaccharide, selective factor Xa inhibitor, a safe and effective antithrombotic agent indicated for preventing thrombus formation in patients with acute coronary syndromes, including those with ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), or unstable angina. Major bleeding is rarely known to exist with the use of fondaparinux and to best of our knowledge there exist no isolated case report presenting with fondaparinux-induced major bleeding prescribed for recently diagnosed NSTEMI. The case report highlights, a need for clinicians to have a sound understanding of anticoagulant pharmacology, dosing, toxicity, individualized approach, and predicting the risk of bleeding before they are prescribed to advancing age persons.
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spelling pubmed-38726732013-12-31 A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml Tandon, Vishal R. Sharma, Sudhaa Mahajan, Shagun Mahajan, Annil Khajuria, Vijay J Midlife Health Case Report Fondaparinux sodium is a synthetic, sulfated pentasaccharide, selective factor Xa inhibitor, a safe and effective antithrombotic agent indicated for preventing thrombus formation in patients with acute coronary syndromes, including those with ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), or unstable angina. Major bleeding is rarely known to exist with the use of fondaparinux and to best of our knowledge there exist no isolated case report presenting with fondaparinux-induced major bleeding prescribed for recently diagnosed NSTEMI. The case report highlights, a need for clinicians to have a sound understanding of anticoagulant pharmacology, dosing, toxicity, individualized approach, and predicting the risk of bleeding before they are prescribed to advancing age persons. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3872673/ /pubmed/24381468 http://dx.doi.org/10.4103/0976-7800.122260 Text en Copyright: © Journal of Mid-life Health http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tandon, Vishal R.
Sharma, Sudhaa
Mahajan, Shagun
Mahajan, Annil
Khajuria, Vijay
A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title_full A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title_fullStr A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title_full_unstemmed A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title_short A rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-ST segment elevation Ml
title_sort rare case of fondaparinux-induced major bleeding in postmenopausal woman prescribed for non-st segment elevation ml
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872673/
https://www.ncbi.nlm.nih.gov/pubmed/24381468
http://dx.doi.org/10.4103/0976-7800.122260
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