Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?

Polyostotic fibrous dysplasia is a rare non-inheritable genetic disease due to mutation in GNAS gene. Here we present two adults who were accidentally detected lytic lesions in spine and after extensive evaluation for malignancies; was diagnosed on biopsy. Current concept of the disease and manageme...

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Autores principales: Gundgurthi, Abhay, Garg, M. K., Bhardwaj, Reena, Kharb, Sandeep, Pandit, Aditi, Brar, Karninder S., Kumar, Ravi, Pandit, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872695/
https://www.ncbi.nlm.nih.gov/pubmed/24381894
http://dx.doi.org/10.4103/2230-8210.122641
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author Gundgurthi, Abhay
Garg, M. K.
Bhardwaj, Reena
Kharb, Sandeep
Pandit, Aditi
Brar, Karninder S.
Kumar, Ravi
Pandit, A. G.
author_facet Gundgurthi, Abhay
Garg, M. K.
Bhardwaj, Reena
Kharb, Sandeep
Pandit, Aditi
Brar, Karninder S.
Kumar, Ravi
Pandit, A. G.
author_sort Gundgurthi, Abhay
collection PubMed
description Polyostotic fibrous dysplasia is a rare non-inheritable genetic disease due to mutation in GNAS gene. Here we present two adults who were accidentally detected lytic lesions in spine and after extensive evaluation for malignancies; was diagnosed on biopsy. Current concept of the disease and management is discussed.
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spelling pubmed-38726952013-12-31 Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery? Gundgurthi, Abhay Garg, M. K. Bhardwaj, Reena Kharb, Sandeep Pandit, Aditi Brar, Karninder S. Kumar, Ravi Pandit, A. G. Indian J Endocrinol Metab Case Report Polyostotic fibrous dysplasia is a rare non-inheritable genetic disease due to mutation in GNAS gene. Here we present two adults who were accidentally detected lytic lesions in spine and after extensive evaluation for malignancies; was diagnosed on biopsy. Current concept of the disease and management is discussed. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3872695/ /pubmed/24381894 http://dx.doi.org/10.4103/2230-8210.122641 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gundgurthi, Abhay
Garg, M. K.
Bhardwaj, Reena
Kharb, Sandeep
Pandit, Aditi
Brar, Karninder S.
Kumar, Ravi
Pandit, A. G.
Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title_full Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title_fullStr Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title_full_unstemmed Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title_short Spinal polyostotic fibrous dysplasia in two adults: Does only biopsy unravel the mystery?
title_sort spinal polyostotic fibrous dysplasia in two adults: does only biopsy unravel the mystery?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872695/
https://www.ncbi.nlm.nih.gov/pubmed/24381894
http://dx.doi.org/10.4103/2230-8210.122641
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