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An unusual case of paraganglioma
Pheochromocytomas or Paragangliomas are neroendocrine tumors elaborating catecholamines. They may not present always in a classic manner and a high degree of suspicion is important in diagnosing them early. They can grow large enough to impinge on the great vessels and yet symptoms may not indicate...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872699/ https://www.ncbi.nlm.nih.gov/pubmed/24381898 http://dx.doi.org/10.4103/2230-8210.122647 |
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author | Sridhar, S. Parghi, V. |
author_facet | Sridhar, S. Parghi, V. |
author_sort | Sridhar, S. |
collection | PubMed |
description | Pheochromocytomas or Paragangliomas are neroendocrine tumors elaborating catecholamines. They may not present always in a classic manner and a high degree of suspicion is important in diagnosing them early. They can grow large enough to impinge on the great vessels and yet symptoms may not indicate the severity until late. A young African 32 year old Male presented with occasional headaches, moderate weight loss, abdominal pain and hypertension for three years. On investigation for hypertension a large paraganglioma was discovered wrapped around the Aorta and vena cava. He was operated successfully after preoperative preparation and was discharged normotensive. CONCLUSION: Young hypertensive should always be worked up fully including checking for abdominal masses. The classic paroxysm was absent in this case. After surgical removal the catecholamines elaborated by the tumor also take time to be washed out of the circulation thus the blood pressure will need careful monitoring. Conventional alpha blockage first and beta blockage later was the algorithm followed but choice of agent was also discussed with nesthethesiologist. Though classically taught phenoxy benzamine is used, in this case it was not used and a combination of Prazosin and Propranolol |
format | Online Article Text |
id | pubmed-3872699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38726992013-12-31 An unusual case of paraganglioma Sridhar, S. Parghi, V. Indian J Endocrinol Metab Case Report Pheochromocytomas or Paragangliomas are neroendocrine tumors elaborating catecholamines. They may not present always in a classic manner and a high degree of suspicion is important in diagnosing them early. They can grow large enough to impinge on the great vessels and yet symptoms may not indicate the severity until late. A young African 32 year old Male presented with occasional headaches, moderate weight loss, abdominal pain and hypertension for three years. On investigation for hypertension a large paraganglioma was discovered wrapped around the Aorta and vena cava. He was operated successfully after preoperative preparation and was discharged normotensive. CONCLUSION: Young hypertensive should always be worked up fully including checking for abdominal masses. The classic paroxysm was absent in this case. After surgical removal the catecholamines elaborated by the tumor also take time to be washed out of the circulation thus the blood pressure will need careful monitoring. Conventional alpha blockage first and beta blockage later was the algorithm followed but choice of agent was also discussed with nesthethesiologist. Though classically taught phenoxy benzamine is used, in this case it was not used and a combination of Prazosin and Propranolol Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3872699/ /pubmed/24381898 http://dx.doi.org/10.4103/2230-8210.122647 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sridhar, S. Parghi, V. An unusual case of paraganglioma |
title | An unusual case of paraganglioma |
title_full | An unusual case of paraganglioma |
title_fullStr | An unusual case of paraganglioma |
title_full_unstemmed | An unusual case of paraganglioma |
title_short | An unusual case of paraganglioma |
title_sort | unusual case of paraganglioma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872699/ https://www.ncbi.nlm.nih.gov/pubmed/24381898 http://dx.doi.org/10.4103/2230-8210.122647 |
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