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Yeast Prions: Protein Aggregation Is Not Enough
Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion?
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387287/ https://www.ncbi.nlm.nih.gov/pubmed/15094820 http://dx.doi.org/10.1371/journal.pbio.0020125 |
Sumario: | Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion? |
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