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Yeast Prions: Protein Aggregation Is Not Enough

Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion?

Detalles Bibliográficos
Autor principal: Sherman, Michael Y
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387287/
https://www.ncbi.nlm.nih.gov/pubmed/15094820
http://dx.doi.org/10.1371/journal.pbio.0020125
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author Sherman, Michael Y
author_facet Sherman, Michael Y
author_sort Sherman, Michael Y
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description Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion?
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spelling pubmed-3872872004-04-15 Yeast Prions: Protein Aggregation Is Not Enough Sherman, Michael Y PLoS Biol Primer Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion? Public Library of Science 2004-04 2004-04-13 /pmc/articles/PMC387287/ /pubmed/15094820 http://dx.doi.org/10.1371/journal.pbio.0020125 Text en Copyright: © 2004 Michael Sherman. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Primer
Sherman, Michael Y
Yeast Prions: Protein Aggregation Is Not Enough
title Yeast Prions: Protein Aggregation Is Not Enough
title_full Yeast Prions: Protein Aggregation Is Not Enough
title_fullStr Yeast Prions: Protein Aggregation Is Not Enough
title_full_unstemmed Yeast Prions: Protein Aggregation Is Not Enough
title_short Yeast Prions: Protein Aggregation Is Not Enough
title_sort yeast prions: protein aggregation is not enough
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387287/
https://www.ncbi.nlm.nih.gov/pubmed/15094820
http://dx.doi.org/10.1371/journal.pbio.0020125
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