Cargando…
Yeast Prions: Protein Aggregation Is Not Enough
Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion?
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387287/ https://www.ncbi.nlm.nih.gov/pubmed/15094820 http://dx.doi.org/10.1371/journal.pbio.0020125 |
_version_ | 1782121303307714560 |
---|---|
author | Sherman, Michael Y |
author_facet | Sherman, Michael Y |
author_sort | Sherman, Michael Y |
collection | PubMed |
description | Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion? |
format | Text |
id | pubmed-387287 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-3872872004-04-15 Yeast Prions: Protein Aggregation Is Not Enough Sherman, Michael Y PLoS Biol Primer Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion? Public Library of Science 2004-04 2004-04-13 /pmc/articles/PMC387287/ /pubmed/15094820 http://dx.doi.org/10.1371/journal.pbio.0020125 Text en Copyright: © 2004 Michael Sherman. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Primer Sherman, Michael Y Yeast Prions: Protein Aggregation Is Not Enough |
title | Yeast Prions: Protein Aggregation Is Not Enough |
title_full | Yeast Prions: Protein Aggregation Is Not Enough |
title_fullStr | Yeast Prions: Protein Aggregation Is Not Enough |
title_full_unstemmed | Yeast Prions: Protein Aggregation Is Not Enough |
title_short | Yeast Prions: Protein Aggregation Is Not Enough |
title_sort | yeast prions: protein aggregation is not enough |
topic | Primer |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387287/ https://www.ncbi.nlm.nih.gov/pubmed/15094820 http://dx.doi.org/10.1371/journal.pbio.0020125 |
work_keys_str_mv | AT shermanmichaely yeastprionsproteinaggregationisnotenough |