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Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study
BACKGROUND: The A(1)chieve, a multicentric (28 countries), 24-week, non-interventional study evaluated the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66,726) in routine clinical care across four continents. MATERIALS AND METHODS:...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872883/ https://www.ncbi.nlm.nih.gov/pubmed/24404475 http://dx.doi.org/10.4103/2230-8210.122062 |
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author | Hajjaji, Issam M. Sherif, Ibrahim Elazrag, Aisha Jaber, Suhair Chakkarwar, Praful N Eltabal, Salem |
author_facet | Hajjaji, Issam M. Sherif, Ibrahim Elazrag, Aisha Jaber, Suhair Chakkarwar, Praful N Eltabal, Salem |
author_sort | Hajjaji, Issam M. |
collection | PubMed |
description | BACKGROUND: The A(1)chieve, a multicentric (28 countries), 24-week, non-interventional study evaluated the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66,726) in routine clinical care across four continents. MATERIALS AND METHODS: Data was collected at baseline, at 12 weeks and at 24 weeks. This short communication presents the results for patients enrolled in biphasic insulin aspart sub group from Libya. RESULTS: A total of 179 patients were enrolled in the biphasic insulin aspart subgroup. All the patients were prior insulin users. At baseline glycaemic control was poor (mean HbA(1)c: 9.3%). After 24 weeks of treatment there was an improvement in HbA(1)c (−0.9%). Hypoglycaemic events reduced from 7.2 events/patient-year to 3.7 events/patient-year in 24 weeks. SADRs did not occur in any of the study patients. CONCLUSION: Starting or switching to biphasic insulin aspart was associated with improvement in glycaemic control with a low rate of hypoglycaemia. |
format | Online Article Text |
id | pubmed-3872883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38728832014-01-08 Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study Hajjaji, Issam M. Sherif, Ibrahim Elazrag, Aisha Jaber, Suhair Chakkarwar, Praful N Eltabal, Salem Indian J Endocrinol Metab Original Article BACKGROUND: The A(1)chieve, a multicentric (28 countries), 24-week, non-interventional study evaluated the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66,726) in routine clinical care across four continents. MATERIALS AND METHODS: Data was collected at baseline, at 12 weeks and at 24 weeks. This short communication presents the results for patients enrolled in biphasic insulin aspart sub group from Libya. RESULTS: A total of 179 patients were enrolled in the biphasic insulin aspart subgroup. All the patients were prior insulin users. At baseline glycaemic control was poor (mean HbA(1)c: 9.3%). After 24 weeks of treatment there was an improvement in HbA(1)c (−0.9%). Hypoglycaemic events reduced from 7.2 events/patient-year to 3.7 events/patient-year in 24 weeks. SADRs did not occur in any of the study patients. CONCLUSION: Starting or switching to biphasic insulin aspart was associated with improvement in glycaemic control with a low rate of hypoglycaemia. Medknow Publications & Media Pvt Ltd 2013-11 /pmc/articles/PMC3872883/ /pubmed/24404475 http://dx.doi.org/10.4103/2230-8210.122062 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hajjaji, Issam M. Sherif, Ibrahim Elazrag, Aisha Jaber, Suhair Chakkarwar, Praful N Eltabal, Salem Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title | Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title_full | Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title_fullStr | Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title_full_unstemmed | Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title_short | Clinical experience with biphasic insulin aspart in people with type 2 diabetes: Results from the Libya cohort of the A(1)chieve study |
title_sort | clinical experience with biphasic insulin aspart in people with type 2 diabetes: results from the libya cohort of the a(1)chieve study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872883/ https://www.ncbi.nlm.nih.gov/pubmed/24404475 http://dx.doi.org/10.4103/2230-8210.122062 |
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