Genome-wide association study identifies a potent locus associated with human opioid sensitivity

Opioids, such as morphine and fentanyl, are widely used as effective analgesics for the treatment of acute and chronic pain. In addition, the opioid system has a key role in the rewarding effects of morphine, ethanol, cocaine and various other drugs. Although opioid sensitivity is well known to vary...

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Detalles Bibliográficos
Autores principales: Nishizawa, D, Fukuda, K, Kasai, S, Hasegawa, J, Aoki, Y, Nishi, A, Saita, N, Koukita, Y, Nagashima, M, Katoh, R, Satoh, Y, Tagami, M, Higuchi, S, Ujike, H, Ozaki, N, Inada, T, Iwata, N, Sora, I, Iyo, M, Kondo, N, Won, M-J, Naruse, N, Uehara-Aoyama, K, Itokawa, M, Koga, M, Arinami, T, Kaneko, Y, Hayashida, M, Ikeda, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873034/
https://www.ncbi.nlm.nih.gov/pubmed/23183491
http://dx.doi.org/10.1038/mp.2012.164

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