Cargando…

Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane

BACKGROUND: Mesenchymal stem cell (MSC) was previously shown to secrete lipid vesicles that when purified by high performance liquid chromatography as a population of homogenously sized particles with a hydrodynamic radius of 55–65 nm reduce infarct size in a mouse model of myocardial ischemia/reper...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Soon Sim, Yin, Yijun, Lee, Tricia, Lai, Ruenn Chai, Yeo, Ronne Wee Yeh, Zhang, Bin, Choo, Andre, Lim, Sai Kiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Co-Action Publishing 2013
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873122/ https://www.ncbi.nlm.nih.gov/pubmed/24371518 http://dx.doi.org/10.3402/jev.v2i0.22614

Ejemplares similares

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA
por: Lai, Ruenn Chai, et al.
Publicado: (2016)

Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome
por: Lai, Ruenn Chai, et al.
Publicado: (2012)

MSC exosome works through a protein-based mechanism of action
por: Toh, Wei Seong, et al.
Publicado: (2018)

Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
por: Loh, Jia Tong, et al.
Publicado: (2022)

Assessment of Tumorigenic Potential in Mesenchymal-Stem/Stromal-Cell-Derived Small Extracellular Vesicles (MSC-sEV)
por: Tan, Thong Teck, et al.
Publicado: (2021)

Function of Platelet Glycosphingolipid Microdomains/Lipid Rafts
por: Komatsuya, Keisuke, et al.
Publicado: (2020)

MSC−sEV Treatment Polarizes Pro−Fibrotic M2 Macrophages without Exacerbating Liver Fibrosis in NASH
por: Zhang, Bin, et al.
Publicado: (2023)

Topical Application of Mesenchymal Stem Cell Exosomes Alleviates the Imiquimod Induced Psoriasis-Like Inflammation
por: Zhang, Bin, et al.
Publicado: (2021)

The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts
por: Komatsuya, Keisuke, et al.
Publicado: (2023)

Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs
por: Chen, Tian Sheng, et al.
Publicado: (2011)

RaftProt V2: understanding membrane microdomain function through lipid raft proteomes
por: Mohamed, Ahmed, et al.
Publicado: (2019)

Lipid Droplets and Their Autophagic Turnover via the Raft-Like Vacuolar Microdomains
por: Rahman, Muhammad Arifur, et al.
Publicado: (2021)

Immunotherapeutic Potential of Extracellular Vesicles
por: Zhang, Bin, et al.
Publicado: (2014)

Generation of Stable Lipid Raft Microdomains in the Enterocyte Brush Border by Selective Endocytic Removal of Non-Raft Membrane
por: Danielsen, E. Michael, et al.
Publicado: (2013)

Lipid Raft Microdomains: A Gateway for Compartmentalized Trafficking of Ebola and Marburg Viruses
por: Bavari, Sina, et al.
Publicado: (2002)

Continuity of Monolayer-Bilayer Junctions for Localization of Lipid Raft Microdomains in Model Membranes
por: Ryu, Yong-Sang, et al.
Publicado: (2016)

HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury
por: Loinard, Céline, et al.
Publicado: (2023)

HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains
por: Ren, Tong, et al.
Publicado: (2013)

Structural and Functional Determinants of AC8 Trafficking, Targeting and Responsiveness in Lipid Raft Microdomains
por: Tabbasum, Valentina G., et al.
Publicado: (2019)

Preferred Endocytosis of Amyloid Precursor Protein from Cholesterol-Enriched Lipid Raft Microdomains
por: Cho, Yoon Young, et al.
Publicado: (2020)

Therapeutic Efficacy of Mesenchymal Stem/Stromal Cell Small Extracellular Vesicles in Alleviating Arthritic Progression by Restoring Macrophage Balance
por: Zhang, Bin, et al.
Publicado: (2023)

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation
por: Watson, Robert T., et al.
Publicado: (2001)

Neuronal KCNQ2/3 channels are recruited to lipid raft microdomains by palmitoylation of BACE1
por: Dai, Gucan
Publicado: (2022)

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
por: Tan, Cheau Yih, et al.
Publicado: (2014)

Dynamics of mitochondrial raft-like microdomains in cell life and death
por: Sorice, Maurizio, et al.
Publicado: (2012)

High Glucose Predisposes Gene Expression and ERK Phosphorylation to Apoptosis and Impaired Glucose-Stimulated Insulin Secretion via the Cytoskeleton
por: Yeo, Ronne Wee Yeh, et al.
Publicado: (2012)

Focus on Extracellular Vesicles: Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles
por: Zhang, Bin, et al.
Publicado: (2016)

Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors
por: Hernaiz-Llorens, Marc, et al.
Publicado: (2020)

O-GlcNAcylation Inhibits Endocytosis of Amyloid Precursor Protein by Decreasing Its Localization in Lipid Raft Microdomains
por: Kwon, Oh-Hoon, et al.
Publicado: (2021)

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
por: Witwer, Kenneth W., et al.
Publicado: (2019)

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains
por: Pavlaki, Nikoleta, et al.
Publicado: (2021)

The Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae Binds to Lipid Raft Microdomains in Human Corneal Epithelial Cells
por: Taylor, Sidney D., et al.
Publicado: (2013)

Mesenchymal stromal cell exosomes enhance dental pulp cell functions and promote pulp-dentin regeneration
por: Shi, Jiajun, et al.
Publicado: (2023)

Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis
por: Jumat, Muhammad Raihan, et al.
Publicado: (2014)

Essential role of ATP6AP2 enrichment in caveolae/lipid raft microdomains for the induction of neuronal differentiation of stem cells
por: Makdissy, Nehman, et al.
Publicado: (2018)

Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution
por: Mattei, Vincenzo, et al.
Publicado: (2011)

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
por: Chen, Tian Sheng, et al.
Publicado: (2010)

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)
por: Ehehalt, Robert, et al.
Publicado: (2008)

Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring
por: Ong, Hon Shing, et al.
Publicado: (2023)

Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5′-Nucleotidase Activity
por: Teo, Kristeen Ye Wen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ft101spm3vg48vlju95o40i5ed