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The PAF Complex and Prf1/Rtf1 Delineate Distinct Cdk9-Dependent Pathways Regulating Transcription Elongation in Fission Yeast

Cyclin-dependent kinase 9 (Cdk9) promotes elongation by RNA polymerase II (RNAPII), mRNA processing, and co-transcriptional histone modification. Cdk9 phosphorylates multiple targets, including the conserved RNAPII elongation factor Spt5 and RNAPII itself, but how these different modifications media...

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Detalles Bibliográficos
Autores principales:	Mbogning, Jean, Nagy, Stephen, Pagé, Viviane, Schwer, Beate, Shuman, Stewart, Fisher, Robert P., Tanny, Jason C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873232/ https://www.ncbi.nlm.nih.gov/pubmed/24385927 http://dx.doi.org/10.1371/journal.pgen.1004029

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