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Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever
BACKGROUND: Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF), is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral therapy for AHF is limited to immune plasma, which is readily available only in the endemic regions of Argentina. T-705...
Autores principales: | Gowen, Brian B., Juelich, Terry L., Sefing, Eric J., Brasel, Trevor, Smith, Jennifer K., Zhang, Lihong, Tigabu, Bersabeh, Hill, Terence E., Yun, Tatyana, Pietzsch, Colette, Furuta, Yousuke, Freiberg, Alexander N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873268/ https://www.ncbi.nlm.nih.gov/pubmed/24386500 http://dx.doi.org/10.1371/journal.pntd.0002614 |
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