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Altered Phase-Relationship between Peripheral Oscillators and Environmental Time in Cry1 or Cry2 Deficient Mouse Models for Early and Late Chronotypes
The mammalian circadian system is composed of a light-entrainable central clock in the suprachiasmatic nuclei (SCN) of the brain and peripheral clocks in virtually any other tissue. It allows the organism to optimally adjust metabolic, physiological and behavioral functions to the physiological need...
Autores principales: | Destici, Eugin, Jacobs, Edwin H., Tamanini, Filippo, Loos, Maarten, van der Horst, Gijsbertus T. J., Oklejewicz, Małgorzata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873389/ https://www.ncbi.nlm.nih.gov/pubmed/24386234 http://dx.doi.org/10.1371/journal.pone.0083602 |
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