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Tandem Repeat Modification during Double-Strand Break Repair Induced by an Engineered TAL Effector Nuclease in Zebrafish Genome
Tandem repeats (TRs) are abundant and widely distributed in eukaryotic genomes. TRs are thought to have various functions in gene transcription, DNA methylation, nucleosome position and chromatin organization. Variation of repeat units in the genome is observed in association with a number of diseas...
Autores principales: | Huang, Wanxu, Zheng, Jianbo, He, Ying, Luo, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873399/ https://www.ncbi.nlm.nih.gov/pubmed/24386347 http://dx.doi.org/10.1371/journal.pone.0084176 |
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