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Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance
Parkinson’s disease (PD) is a movement disorder associated with genetic and age related causes. Although autosomal recessive early onset PD linked to parkin mutations does not exhibit α-Synuclein accumulation, while autosomal dominant and sporadic PD manifest with α-Synuclein inclusions, loss of dop...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873413/ https://www.ncbi.nlm.nih.gov/pubmed/24386307 http://dx.doi.org/10.1371/journal.pone.0083914 |